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Throughout the 1980s and 1990s, researchers in Europe and Russia conducted numerous studies on DSIP, examining everything from its effects on insomnia to its potential role in pain management and substance withdrawal

During an innate immune response, the PRR Nod2 senses unique pathogen-derived PAMPs and, as a consequence, induces NFB and MAPK activation and a subsequent release of proinflammatory mediators

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[DOI] [PubMed] [Google Scholar] Selepe MA, Kunyane P, Seboletswe P, Nair S, Cele N, Engelbrecht M, Joubert DF, Vandevoorde C, Singh P, Sonopo MS

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