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Conclusion .It also provides further evidence that participation in audit can bring about change in clinical behaviour leading to improvements in standards of care Use of vitamin B12 injections among elderly patients by primary care practitioners in Ontario although therapy for vitamin B12 deficiency prevents serious morbidity clinical audits in Britain have shown that approximately half of the patients receiving regular vitamin B12 injections do not meet explicit criteria supporting its use and up to one fifth of patients receive unnecessarily frequent injections

That is a fraction of what the mouse data would predict if the compound translated 1:1, but allometric scaling rarely works that cleanly and community doses are below the mouse-equivalent scale

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