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Therefore, we assumed that the PI3K/Akt pathway was involved in the GHK-induced upregulation of miR-146a-3p and that the miR-146a-3p/AQP4 axis played a role in manipulating astrocytes following ICH injury

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Other studies have demonstrated a dose-dependent effect of acetyl-l-carnitine in counteracting oxidative stress caused by arsenic and improved mitochondrial function in a rat hippocampus model and reduced the levels of free radicals induced by cuprizone in murine corpus callosum [21, 22]

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Ly C, Greb AC, Vargas MV, Duim WC, Grodzki ACG, Lein PJ, et al