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Am J Reprod Immunol (2019) 82(3):e13151

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In less common cases, more serious risks such as pancreatitis, gallbladder-related issues, or kidney complications may occur, particularly in individuals with underlying medical conditions

Recent epigenetic genome-wide analysis identified low HIF3A methylation levels upregulates HIF3A expression in adipose tissue, thereby leading to adipose tissue dysfunction and adiposity