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[DOI] [PMC free article] [PubMed] [Google Scholar] Fraternate A, Paoletti AF, et al

Across oncology, cardiometabolic disease, liver and rare disorders, several late-stage readouts stood out not because they met endpoints, but because they reset expectations introducing new standards of care, validating new platforms, or delivering benefits where progress had stalled for decades

10.1016/j.ejphar.2012.07.031 Eur