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Archives of Pharmacal Research

Interestingly, previous transcriptional analysis uncovered that AITC treatment affected the expression profile of certain genes involved in the regulation of cell cycle 23 , indicating the phytochemical-induced growth inhibition might be an indirect consequence of cell cycle misregulation due to GSH depletion

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Minerva Gastroenterol Dietol

After that, in order to validate the model, we simulate the system of equations with the estimated parameter values and calculate goodness of fit of the [GSH] and [GSSG] simulation results to the validation set

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