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L., & Woo, V

Chemical modification of metformin into sulfenamides and sulfonamides has also improved the cellular accumulation of these compounds in cancer cells, with a subsequent increase in their cytotoxic efficacy

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It may help to distinguish certain disorders affecting the small nerve fibers, such as painful sensory neuropathies affecting nerve fibers called axons

However, MT-2 has been studied primarily as a research compound, not as an FDA-approved obesity therapy, so long-term human data at standardized doses doesn't exist