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LIMITATIONS This Phase 2 study had several limitations, including the small sample size and limited followup period of 36 weeks

They also mitigate Nf-B overactivated signalling, attenuating the NLRP3 inflammasome pathway and decreasing pro-inflammatory cytokines and PCR levels, thereby showcasing their immunomodulatory activities [161, 202, 217]

The reconstituted solution is more vulnerable to degradation than the lyophilized powder

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