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Journal of immunology (Baltimore, Md: 1950) 2012;188:1503-13

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101 Data on the NAC effects in COPD suggest that NAC reduces elastase activity, 99 hinders the loss of pulmonary glutathione, abolishes the effects of cigarette smoke, prevents thickening of the airway wall, and reduces the risk of exacerbations

So, if youve had excess adipose on you for a long time, eventually it will become pro-inflammatory and you will walk into metabolic dysfunction