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Women with PCOS may experience a decline or halt to ovulation, increased testosterone levels, and insulin resistance, leading to metabolic dysfunction and cardiometabolic disease

10.1016/j.clnu.2019.01.020 26

(2016) Nuclear localization of glutamate-cysteine ligase is associated with proliferation in head and neck squamous cell carcinoma, Oncol

Lancet 405 , 15801593 (2025)

The mechanisms most cited in the literature are promotion of angiogenesis (new blood-vessel formation, linked to VEGFR2 signaling), modulation of growth-factor and nitric-oxide pathways, and interaction with the gut-brain axis