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Pathological -synuclein exacerbates the progression of Parkinsons disease through microglial activation

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(44) pointed out that nitric oxide synthase (NOS) mRNA was positively correlated with the representative level of oxidative stress in the organism, SOD, in the lens of cortical cataract patients

(2) activation of pro-apoptotic proteins resulting in induction of apoptosis

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The high stability of the structural disulphide bonds found in the IMS (redox potentials in the range of 320 mV) and the low redox potential of the active site cysteine pair of the oxidoreductase Mia40 (290 mV