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Clinical gastric emptying studies show tirzepatide delays solid food emptying by 3542% at therapeutic doses, compared to 2028% for semaglutide at equivalent weight loss efficacy

The activation of the post-receptor signaling cascade induced by GLP-1 and GLP-1 receptor agonists and the consequent modulation of insulin signaling pathway would reduce storage of hepatocyte triglyceride and consequently improve hepatic steatosis [83]

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The question is what it delivers per dollar spent