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GlcNAcβ(1-4) Man-α-O-7-Methylcoumarin
/ Fmoc-Ser((Ac)3-Fuc-β-L)-OH / Fmoc-Ser(β-L-Fuc)-OH (Peracetate)
The installed glycan is a fucose residue (O-fucosylation)
This compound presents the Blood Group A trisaccharide (GalNAcα1-3[Fucα1-2]Gal)
and inhibitor / activator studies
GA731000: Fmoc-Thr((Ac)3-Fuc-α-L)-OH Pack Size:100 mg GlcNAcβ(1-4) Man-α-O-7-MethylcoumarinC31H35NO12 613. 61 An Fmoc protected L threonine building block carrying an L fucose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as three acetate esters (Ac3), which keep the glycan inert
