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M., Joensen, F., Hougaard, D

It typically resolves on its own without treatment

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SAG administration, thanks to its ability to maintain a cellular reductive state, enhanced antioxidants, including Nrf2, HO-1 and NQO-1, and restored SOD activity and GSH levels in the liver as well

In cardiac cells, the physical proximity between mitochondria and the sarcoplasmic reticulum (SR, a specific type of ER in heart and skeletal muscle cells) allows the exchange of Ca 2+ in local microdomains, providing rapid Ca 2+ buffering

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