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In addition, GSH depletion and GSSG accumulation due to oxidative stress induce apoptosis by activating the SAPK/MAPK pathway [18]

Appropriate inflammatory balance is especially important during ischemic injury, where there is major neuronal death and without proper neuroprotective measures, progressing injury can have detrimental effects on functional outcome and survival

Engrafted glial progenitor cells yield long-term integration and sensory improvement in aged mice

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo