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The failure of macrophages to clear apoptotic cells contributes to prolonged inflammation, as these unengulfed cells can undergo secondary necrosis, releasing inflammatory mediators that exacerbate tissue damage and promote a new cycle of inflammation (134, 135)
However, this approach sacrifices convenience and is typically unnecessary given BPC-157's reasonable 28-day refrigerated shelf life
Some people benefit from weekly shots, while others do better with monthly sessions
It also has effects on appetite, libido, and other melanocortin-mediated pathways
doi: 10.1111/j.1749-6632.1982.tb31231.x 197