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Consistency and bioavailability are the two biggest factors in how quickly you will notice a change

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the agency said in December that its Pharmacovigilance Risk Assessment Committee was seeking more information from the drugs makers, and that while at this point no conclusion can be drawn on a causal association, there are several issues that still need to be clarified. Late last week, a large review of electronic health records from the US found that GLP-1 drugs actually carried a lower risk of patients having suicidal thoughts compared with other medicines that work in different ways for diabetes and weight loss

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Reported side effects include digestive symptoms like nausea and constipation (28)