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Briefly, the recognition of SECIS by the translational machinery results in the recruitment of specific translational factors that decode in-frame UGA codons by inserting selenocysteine into elongating selenoproteins (4)

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Increasing concentrations of HQ in the presence of L-tyrosine, resulted in an increase in the K m value while the V max remained constant, an indication of a competitive inhibition mode on the monophenolase activity, with a K I of 40 M and apparent K m and V max values of 0.07 mM and 9.0 mole min 1 mg 1 , respectively (Fig