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Amylin acts primarily on the brainstem and hypothalamusareas of the brain that regulate hunger, satiety, and energy balance

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Addressing its poor solubility, rapid metabolism, and low membrane permeability through delivery systems including nanocarriers may prove beneficial, but research is limited

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Muscle PARP1 inhibition extends lifespan through AMPK PARylation and activation in Drosophila

J Korean Soc Coloproctol