Maahs D, de Serna DG, Kolotkin RL, Ralston S, Sandate J, Qualls C, et al
Wakabayashi H, Yamauchi K, Takase M
PT-141 (Bremelanotide) - Libido and sexual function The menopause libido solution: Libido often crashes during/after menopause Traditional solutions (testosterone, HRT) have side effects PT-141 works differently - activates desire pathways in brain Benefits: Restored sexual desire and arousal Works in 60-80% of women No hormonal side effects Can use as needed (not daily) Protocol: 0.5-2mg injected subcutaneously Take 2-3 hours before desired effect Use as needed (1-3x weekly typical) Effects last 6-12 hours Side effects: Mild nausea (20-30% of users, temporary) Flushing (common, temporary) Usually tolerable and worth it for benefit Cost : $40-80 per dose, use as needed = $160-240 monthly if using weekly Game-changer : Many menopausal women report this dramatically improves quality of life and relationships
(2001) Post-prandial decrease of circulating human ghrelin levels
The average recorded weight loss per patient is about 8-12 lbs
Significantly greater reductions in HbA1c from baseline to week 26 were reported for all doses of oral semaglutide except the 3 mg dose compared to sitagliptin
