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Similar immune-mediated tumor regression was reported in rats injected with IGF-1R-depeted HGG cells, findings that triggered a pilot clinical trial and a Phase IIb trial (NCT04485949) 14,15,16

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29.9% of patients taking 100-mg Resmetirom show MASH resolution (Harrison et al

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Osteomalacia, a condition involving the softening of bones due to impaired mineralization, was rare but occurred about twice as often in the GLP-1 group