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The revised answer should stay focused on laboratory protocol differences rather than consumer administration advice

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Mechanism 1: Mitochondrial Oxidative Stress EGCG at high concentrations generates reactive oxygen species (ROS) inside hepatocytes, a mechanism documented in multiple cell-culture and rodent studies [7]

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Sun C, Wang K, Stock AJ, Gong Y, Demarest TG, Yang B, Giri N, Harrington L, Alter BP, Savage SA, Bohr VA, Liu Y (2020) Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction