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Shannons group is the first to demonstrate that infusion of GLP-1(7-36) (1.5 pmol/kg/min) for 72 hr in patients with left ventricular dysfunction after MI improved global and regional left ventricular wall motion scores and reduced hospital stay and in-hospital mortality

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Neuroplasticity driven by HGF/c-Met signaling includes upregulation of brain-derived neurotrophic factor (BDNF), activation of postsynaptic density protein-95 (PSD-95), and increased expression of GluN2B-containing NMDA receptors

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But if there isnt enough ascorbic acid available, the collagen strands are underhydroxylated and instead of forming strong tropocollagen, the underhydroxylated collagen is degraded as shown below

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