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In the US, out-of-pocket costs for monthly weight loss injections routinely exceed $1,000 to $1,300 due to severe pharmacy price markups and strict insurance restrictions

With the aim of identifying patterns of co-regulated genes in a way that is neither fully data-driven nor fully constrained by biological knowledge, Pathway-level information extractor (PLIER) (Mao et al., 2019) was used

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Across multiple studies, BPC-157 consistently decreases levels of pro-inflammatory cytokines like TNF- and IL-6

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Metformin remains an important anchor potential alongside GLP-1RAs- enhancing biological efficacy, improving tolerability, and sustaining metabolic and weight benefits