Wagner et al., 2002)
All of the aforementioned saponins effectively alleviate organ damage induced by their corresponding chemotherapeutic agents (e.g., cisplatin, doxorubicin, and CPT-11), as evidenced by improved organ function, attenuated histopathological injury, and decreased levels of relevant damage markers
4A), indicating the potential of these conjugates to serve as relevant clinical markers when blood samples are available, as it is in the case of acute intoxication, to monitor the elimination of the toxic NAPQI
GHK-Cu is a chemical substance intended exclusively for research purposes
Compared with fulllength TB500, the fragment shares the same peptide sequence (LKKTETQ) but lacks an aldehyde group on the leucine residue, a difference that reduces its molecular weight (889.0 vs 846.97 g/mol) and is proposed to increase stability, prolong halflife, and reduce offtarget interactions
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