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Novo Nordisk maintains that the benefit-risk profile of semaglutide, the active ingredient in Ozempic, is unchanged and emphasizes its commitment to patient safety

Mice with the NLGN3-R451C mutation exhibit social deficits and behavioral problems, with increased excitatory synaptic transmission in the CA1 region of the hippocampus and enhanced inhibitory synaptic transmission in the 2/3 layers of the somatosensory cortex (86).Enhanced inhibitory synaptic transmission in Purkinje cells is manifested as an increase in the amplitude of mIPSCs, with no significant change in frequency (87)

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Possible small weight loss (2-5 pounds over 3 months) when combined with lifestyle changes

Guillermo Ponce de Leon-Ballesteros, Department of Surgery, Hospital Star Medica Morelia, Morelia, Michoacan, Mexico

As with any medication, semaglutide carries a risk of side effects