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In this context, collected data are presented to manifest that sulfonylureas are capable of impacting other ion channels besides K ATP channels, such as TRP and BK Ca , via direct and indirect ways, exhibiting the involvement of diverse ion channels in the modulation of insulin secretion and antidiabetic actions (see Table 1)

doi: 10.1016/j.cmet.2006.10.001 26 FuscoJXiaoXPrasadanKShengQChenCMingY-Cet al

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