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Semaglutide is typically administered as a once-weekly injection

Results Thirty one studies 13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43 were selected after following inclusion and exclusion criteria

Retatrutide, a GLP-1/GIP/glucagon triple agonist, is investigational and not FDA-approved as of April 2026, so it is not a current weight-loss option

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This process succeeds in approximately 70% of cases with proper medical justification