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Thats reasonable for a low-risk topical product but should temper expectations

While the typical dermaroller used for treating acne scars is a drum-shaped device equipped with 192 fine microneedles arranged in eight rows and 36 columns ranging from 0.5 to 1.5 mm in length and diameter of 0.1 mm, the dermaroller used in this study had 540 needles with 1.5 mm length titanium needles

doi: 10.2147/IJN.S225807

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Palinski W., Rosenfeld M

All semaglutide injections are subcutaneous preferred sites are the lower abdomen, outer thigh, and outer upper arm, rotating weekly to minimize local reactions