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142 The potential downstream pathways of oligomers on neurons and glial cells are illustrated in Fig

To facilitate purification of homogeneous protein complexes and cryo-EM grid preparation, we truncated the N-terminus of CDK11, generating CDK11 p58 (CDK11B p110 residues 357795) and removed the C-terminal tail of cyclin L2, including its predicted disordered RS-domain, resulting in expression of cyclin L2 residues 1319 (Supplementary Fig

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