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Recent phase 2 clinical trial data evaluating the activity and safety of Retatrutide in subjects with type 2 diabetes demonstrate its pronounced effects on both glycemic control and body weight reduction

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Peterli et al., 2012), which may be due to an increase in the number of L cells or in their secretion, or may reflect the flow of nutrients to more densely populated areas of L cells in the distal small intestine

Although the average weight loss on Wegovy can vary, clinical trials show that patients can lose up to 15% of their starting body weight at the highest dose over 68 weeks