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Demonstrate pen use and have patients perform return demonstration

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Western blot (WB) results revealed a significant increase in the expression of Ki-67 and Lamin B, while the protein levels of P21, P16, and -H2AX decreased following FOXO4-DRI treatment (Figure 4A)

Oncology 64 , 341345 (2003)

131 This is consistent with the data in humans showing that a low-protein diet (5E% protein) increased plasma FGF21 concentrations by 171% over 4 weeks despite caloric overfeeding

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