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Acetaminophen has a very high oral bioavailability of 6088% ( C max ) is 12.3 g/ml, area under the curve over 6 h (AUC 06 ) is 29.4 g/h/ml, and AUC extrapolated to infinity (AUC 0 ) is 44.4 g/h/ml

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Some biomarkers (oxidative stress, antioxidant capacity) may shift within 24 weeks, while functional improvements may take 812 weeks or longer depending on dose, route, and baseline status

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