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RETURN TO TOP May 28, 2017: EPIC study's bluster about pimobendan unravels as critical analysis finally takes hold EPIC's recommendation to start pimobendan at the first sign of heart enlargement, is rejected for a "more measured approach" Retract and re-write this ticking time-bomb before it is too late

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A 2018 systematic review and meta-analysis identified 20 randomized controlled trials (published between 2007 and 2017) that examined the effect of supplemental lipoic acid on markers of glucose utilization in 1,245 subjects with metabolic disorders (not limited to type 2 diabetes) (60)