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These include standardizing vitamin D assays, better characterizing baseline vitamin D status, and accounting for genetic factors that influence vitamin D metabolism

Despite the widespread morbidity and mortality burden of HFpEF, current treatment options are limited, said corresponding author Nils Krger, MD, of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Womens Hospital, a founding member of the Mass General Brigham healthcare system

TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell-fate decision

Findings indicated reduced lipid deposition, increase in metabolites associated with -oxidation, and significant reduction in fatty acid levels in the liver, implying improvement in fatty liver condition