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Russo, 2013

The related Athira compound fosgonimeton failed its Phase 2 Alzheimer's trial (LIFT-AD) in 2023 for efficacy, and Athira discontinued development

Potential Effects on Fat Storage: Emerging research suggests GLP-1 medications may also influence how your body stores and processes fat, although this effect is less pronounced than their impact on appetite and calorie intake

Starting one at a time before adding the second can help you gauge your individual response to each

Dermal lipogenesis inhibits adiponectin production in human dermal fibroblasts while exogenous adiponectin administration prevents against UVA-induced dermal matrix degradation in human skin

The clinical significance of this added increase in serum creatinine relative to placebo is not known