doi:10.3389/fphar.2023.1327230 17
Besides, TECs from patients with DKD exhibited a significant increase in immunostaining levels of TLR4, GSDMD, NLRP3, IL-1, and IL-18, which are common markers for pyroptpsis (124, 126, 127)
Specifically, the use of chemotherapy drugs resulted in elevated levels of ALT and AST, and an increase in the severity of side effects such as nausea and vomiting, contributing to high GSH intake
All in all, balance of redox regulators is essential for health across all life forms, and their pools are consumed or imbalanced as a consequence of diseases
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Nrf2-dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin-induced cardiotoxicity