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To understand whether there is a difference in NSAID usage between sexes, we compared the first records of NSAID usage in VUMC SD (Fig

Sleep loss increases cortisol

A water-soluble iodinated contrast agent (e.g., iohexol, Gastrografin) is preferred if there is any risk the esophagus is perforated, because these agents are less irritating and more rapidly reabsorbed

Knowing that a slower pace is expected helps prevent strict diets or unhelpful changes that can make progress harder

Addition of ammonium bicarbonate prior to the protein precipitation step to increase recovery to 100%

What I appreciated most was how manageable the process felt compared to previous approaches I had tried