Originally developed to treat Type 2 diabetes, GLP-1 receptor agonists gained attention when clinicians noticed that patients taking them were also losing a meaningful amount of weight
doi: 10.1146/annurev-immunol-051116-052424 97
The Three Generations of Incretin Peptide Research The progression from single to dual to triple agonist peptides represents a research trajectory that has played out in roughly ten years: Generation 1 Single GLP-1 Agonists (Semaglutide, Liraglutide, Exenatide) The first incretin peptides to reach broad clinical research were GLP-1 receptor agonists
& Wein, A
In particular, CJC-1295 has been demonstrated to preserve growth hormones physiologic effects on hyperplasia, hypertrophy, bone density, blood sugar, fat metabolism, protein synthesis, and myocardial (heart cell) function
Its balanced formula combines glutathione, PDRN, and a peptide complex to help the skin look smoother, fresher, and more radiant without a heavy feel