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Treatment requires medical evaluation and prescription
Initially, the body compensates for this by enhancing insulin secretion leading to abnormally high concentrations of insulin in the blood, a condition called hyperinsulinemia
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It also attaches to the GLP-1 receptors in the brain and the gut to signal that you're full
GLP-1 receptor agonists e.g., semaglutide, liraglutide commonly cause gastrointestinal adverse effects such as nausea, vomiting, diarrhea, constipation, and abdominal discomfort, especially during dose escalation, less common risks include pancreatitis, gallbladder disease, and hypoglycemia mainly with insulin sulfonylureas
Butsch, who has previously consulted for Novo Nordisk (maker of Wegovy) and Eli Lilly (maker of Zepbound), said he was already concerned about the ubiquity of compounded semaglutide and tirzepatide in recent years
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