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Three interconnected pathways function as core suppressors of ferroptosis: (1) the GPX4-GSH system (central suppressor), (2) the SLC7A11-cystine import pathway (GSH synthesis), and (3) the AIF family member 2 (AIFM2, also known as FSP1)-NAD(P)Hquinone pathway (parallel protection) 84-87
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Nishimoto, S., H
It possesses multiple biological activities, including antioxidant, anti-inflammatory, and neuroprotective effects
Glutamine deprivation counteracts hypoxia-induced chemoresistance
Research thus far has been done in adults with type 2 diabetes whose blood sugar remains high despite lifestyle changes and adults with obesity or overweight who do not have diabetes What is orforglipron approved for
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