Consumers should perform this search themselves because regulatory status changes and a review article cannot reflect actions taken after its publication date
The EMAs Pharmacovigilance Risk Assessment Committee (PRAC) reviewed available data and officially concluded that NAION is a very rare side effect of semaglutide, recommending an update to product information
The study also confirmed previous findings that GLP-1 receptor agonists protect cardiovascular health, with a 14% reduction in the risk of cardiovascular death, non-fatal heart attack, and non-fatal stroke, compared to placebo
We are living in an era with unprecedented access to data, technology, and knowledgeyet, paradoxically, we sometimes seem to drift away from them in our decision-making processes
Consideration should be given to changing the therapeutic regimen, including possibly discontinuing the medication, in patients whose depression is persistently worse, or who are experiencing emergent suicidality or symptoms that might be precursors to worsening depression or suicidality, especially if these symptoms are severe, abrupt in onset, or were not part of the patients presenting symptoms
Denicola et al., 2015)
