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Beyond Parkinsons, L-DOPAs therapeutic potential extends to neurodegenerative conditions such as Alzheimers disease, Huntingtons disease, multiple sclerosis, Lewy body dementia, and amyotrophic lateral sclerosis, where dopamine modulation plays a critical role

Next, we examined the effect of regulating GPX1 expression by ebselen or GPX1 deficiency on peroxynitrite-induced SGNs loss

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1998;274(2):L25863

Chang S, Ren G, Steiner RD, Merkens L, Roullet JB, Korade Z, et al