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In the end, the question is not simply whether metformin should be stopped, but rather: Which patient, at what stage, and under what conditions might patients still benefit from metformin continuation

Historical approval rate for obesity drugs reaching PDUFA stage: ~7080%

[2] Additional trials in type-2 diabetes and liver-fat conditions have also been reported

That growth has already been enjoyed by shareholders of the companies dominating that space, including Novo Nordisk NYSE: NVO, maker of Ozempic and Wegovy, and Eli Lilly NYSE: LLY, maker of Zepound and Mounjaro

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