Under conditions of metabolic stress, it migrates to the cell nucleus, where it activates a suite of genes governed by AMPK (AMP-activated protein kinase), the master cellular energy sensor
doi: 10.1210/jc.2006-2003
2019 Endocrinology GH/IGF-1 Axis Research model for studying GHRH receptor pharmacology, GH secretagogue effects, and downstream IGF-1 modulation in the context of GH deficiency states and aging-related GH decline
People with SLE may have an increased risk of developing type 2 diabetes, a disease that causes your glucose (blood sugar) levels to be too high
Several pathways are required to maintain redox homeostasis, in particular the glutathione-glutaredoxin and thioredoxin-thioredoxin reductase systems 1
Once in the bloodstream, B12 attaches to transporter proteins, like holotranscobalamin (TC-Cbl), which carry it to cells where it supports functions such as DNA synthesis, cell growth, and energy production