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Furthermore, CJC-1295 is believed to increase plasma IGF-I concentrations by 1.5- to 3-fold

(2019) 63:e1801407

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These pathway-level predictions were experimentally validated, as PYC significantly suppressed IL-6 and IL-1 expression in lipopolysaccharide-induced BV2 microglial cells, supporting its multi-component, multi-target mode of action (Liu et al., 2024)