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mtROS are generated by inefficient electron transfer through the ETC 104 , and defects in the ETC have been shown to increase mtROS even further 105

Klein A, Schiffner R, Schiffner-Rohe J, Einsele-Kramer B, Heinlin J, Stolz W, Landthaler M

A 2-year randomized controlled trial with low-dose B-vitamin supplementation shows benefits on bone mineral density in adults with lower B12 status

10.1016/0893-133x(95)00137-3 73 MarkK

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Potential Side Effects Of Glutathione Glutathione is generally considered safe