Although there is a tendency to refer definitively to mechanisms of neutralization in the literature from structural studies on recombinant proteins, it is worth emphasizing that these may be hypotheses that would require detailed and difficult studies to be truly definitive
Brackman and Coenye 2015
Nat Rev Genet 21(4):255272 Robbins PD, Tahara H, Ghivizzani SC (1998) Viral vectors for gene therapy
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Wrasidlo W, Crews LA, Tsigelny IF, Stocking E, Kouznetsova VL, Price D, et al
Conclusion and Future Perspectives The beneficial or detrimental effects of estrogens on NSPCs biology and neurogenesis, and their effects on neuronal function and survival represent a challenging research field