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07851, STEMCELL Technologies) followed by centrifugation at 400 g for 25 min at room temperature at 0 break and 0 acceleration

10.1371/journal.pone.0035823 Summary Keywords clinical applications, glycyrrhizin, glycyrrhizin preparations, liver disease, pharmacological mechanisms, safety Citation Ma T, Hao H, Wang S, Qiu D, Cao W, Deng W, Wang S, Li X, Zhang Z, Wei X, Yao L, Gao Z, Yi W, Liu R and Li M (2026) Glycyrrhizin preparations in liver diseases: a narrative review of mechanisms and therapeutic potential

It is the active ingredient in Novo Nordisk's Wegovy (weight management indication) and Ozempic (diabetes indication)

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These include high-fat meals, alcohol, and grapefruit juice

When tissues sustain damage, GHK-Cu is released from extracellular matrix proteins including SPARC and collagen, functioning as a matrikine, a signal molecule that activates repair mechanisms