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Injuries included were ulcerative colitis, Crohns disease, colitis, inflammatory bowel disease, irritable bowel syndrome, rectal bleeding, diarrhea, abdominal pain, or other injury. Suicide, IBD and Other Injuries Related to Accutane While some people who sued Roche blamed Accutane for psychosis, depression and suicide, most lawsuits claimed the drug caused IBD
US FDA has been sending warning letters for manufacturing and quality control lapses to Indian firms like Cadila Pharmaceuticals (2014, 2016, 2019), Glenmark Pharmaceuticals (2019-2025), Zydus Lifesciences (2024), Kilitch Healthcare (2024) and Natco Pharma (2024), among others
It also supports phase II liver detoxification during sleep, reducing the burden of accumulated toxins and metabolic byproducts
Acknowledgments We would like to thank all researchers that provided to the topic in other organisms and all authors that were not cited
